Denise Esserman

Denise Esserman is a Professor of Biostatistics at the Yale School of Public Health, where she joined the faculty in 2014. She is a member of the Yale Center for Analytical Sciences and collaborates with multiple departments at the Yale School of Medicine, including the Clinical and Translational Science Award Program, Patient-Centered Outcomes Research Institute, and the Cancer Center. Her research focuses on methodological aspects of clustered randomized trials and sample size calculations.

Education:

• PhD in Biostatistics from Columbia University (2006)
• MS in Statistics from University of Georgia (2001)

Dr. Esserman's research interests span several critical areas in biostatistics and public health methodology. She specializes in clustered randomized trials, with particular expertise in understanding how intraclass correlation coefficients (ICC) and other factors impact sample size calculations. Her work extends to longitudinal studies methodology, randomized controlled trial design, and sampling techniques. She has contributed significantly to statistical methods for clinical trials, healthcare data analysis, and public health research. Her interdisciplinary approach bridges theoretical statistics with practical applications in healthcare settings.

Analysis of Dr. Esserman's recent publications reveals a strong focus on methodological innovations in clinical trial design and analysis, particularly for cluster-randomized trials. Her work spans healthcare applications including fall injury prevention in elderly populations, opioid use disorder treatment in international settings, pain management for hemodialysis patients, and validation of medical coding algorithms. She frequently employs advanced statistical techniques including Bayesian methods, mediation analysis, and methods for handling clustered data. Her research demonstrates a consistent commitment to improving the rigor and applicability of statistical methods in public health and clinical research.

Dr. Esserman serves as a reviewer for several prestigious journals including the American Journal of Epidemiology, Arteriosclerosis, Thrombosis and Vascular Biology; Statistics in Biopharmaceutical Research; Clinical Trials; and Obesity.

As a member of the Yale Center for Analytical Sciences, Dr. Esserman collaborates with numerous researchers across Yale University. Her current projects include the EQuIP trial (HIC ID 2000033355), where she serves as Sub Investigator with primary completion date of 08/31/2027, focusing on mental health and behavioral research for sexual minority women.