David Zidar

Dr. David Zidar, an Associate Professor in the Department of Pathology at Case Western Reserve University School of Medicine, leads the Zidar Laboratory focusing on the interplay between immunohematologic dysregulation and cardiovascular disease. His research integrates population-level observations with translational studies on sterile (e.g., metabolic, neuro-endocrine) and infectious (e.g., HIV, SARS-CoV-2) processes affecting vascular health. Key interests include biomarker-driven patient stratification and global health implications of inflammatory disorders. Clinically active as an Interventional Cardiologist, he serves on the executive scientific board of the Harrington Discovery Institute and mentors emerging leaders in cardiology.

Research emphasizes biomarkers such as platelet aggregates, erythrocyte phenotypes, and multi-omic profiles to identify patient endotypes for precision medicine. His work bridges basic science and clinical practice, addressing cardiovascular risks in conditions like rheumatoid arthritis, aortic stenosis, and post-COVID-19 sequelae. Over 100 publications highlight contributions to renal denervation trials, biomarker validation, and HIV-related cardiovascular complications.

• Teaching Awards: Recognized for educational excellence in medical training.
• Professional Memberships: American College of Cardiology, Society for Cardiovascular Angiography and Intervention.
• Labs/Teams: Zidar Laboratory, Center for Global Health and Diseases.

Current projects explore aging-related immunohematologic resilience, SARS-CoV-2 cardiovascular impacts, and novel antihypertensive therapies. His translational approach aims to reduce mortality through early biomarker detection and personalized interventions.