David Tougeron

Professor David Tougeron is a Digestive Oncologist at Poitiers University Hospital and holds a Professorship at the University of Poitiers (Faculty of Medicine and Pharmacology). His expertise spans colorectal carcinogenesis, microsatellite instability, anti-tumor immunity, and immuno-oncology. He leads clinical trials in digestive oncology, particularly focusing on biomarkers like ctDNA and brain metastasis of colorectal cancers. His translational research includes national cohort studies (e.g., METACER) and basic science investigations into metastasis biology. Key collaborations include the ENGIC European network and PRODIGE clinical trials. He is affiliated with the PRODICET Laboratory (UR 24144), specializing in tumor cell dissemination research.

Research interests emphasize predictive/prognostic biomarkers, clinical trial design, and molecular mechanisms of metastasis. His work bridges experimental biology and clinical practice, addressing unmet needs in gastrointestinal cancers. Recent publications highlight ctDNA utility in treatment monitoring and combination immunotherapy efficacy.

Grants and clinical trials include studies on anti-EGFR/VEGF therapies, BRAFV600E mutations, and pancreatic cancer regimens. His lab focuses on Hepato-gastroenterology with ties to the PRODICET team exploring TAM receptors and exosome roles in metastasis.