David Pilgrim

David Pilgrim is a Professor in the Department of Biological Sciences at the University of Alberta. His research focuses on developmental neurobiology, sex determination pathways, and myosin assembly mechanisms using C. elegans and zebrafish as model organisms. He leads the Pilgrim Lab, which investigates genetic and cellular processes critical for development and differentiation.

Research Highlights:

• Sex determination pathway analysis in C. elegans, particularly the role of FEM-2 phosphatase in signaling between TRA-2 and TRA-1.
• UNC-119 protein’s role in neurogenesis, axon guidance, and cytoskeletal regulation across species.
• UNC-45’s dual role in muscle development and cytokinesis, linking it to human muscle disorders.

Dr. Pilgrim teaches advanced genetics courses, including GENET 270 (Molecular Genetics), GENET 412/512 (Genetic Control of Animal Development). His work bridges basic science and medical relevance, leveraging genetic tools for mechanistic insights.