David Fox

David Fox is a Professor of Rheumatology and Internal Medicine at the University of Michigan Medical School, where he has held leadership roles including Division Chief and directs the NIH-funded Clinical Autoimmunity Center of Excellence and Hybridoma Core facility. His research focuses on T cell activation mechanisms in autoimmune diseases like rheumatoid arthritis and scleroderma.

• Undergraduate: MIT (1974)
• M.D.: Harvard Medical School (1978)
• Training: Brigham and Women's Hospital, Dana-Farber Cancer Center

Research Highlights: Pioneered monoclonal antibody approaches to identify T cell-synovial fibroblast interactions (CD60, CD6 ligands), defined IL-17's role in arthritis, and explored dendritic cell immunoregulation in murine models. Current work bridges autoimmune disease and cancer immunotherapy through CD6-targeted therapies.

Scientific Recognition: 200+ publications, past President of the American College of Rheumatology, editorial leadership in top journals, and NIH funding. His lab's discoveries inform novel treatments for arthritis and fibrosis.

• Key advisees: Rachel Morgan, Matthew Klinker, Laura Cooney, Chinh Tran
• Collaborations: Dana-Farber Cancer Center, NIH, World Scleroderma Foundation