David Engelberg

Prof. David Engelberg is a Professor in the Biological Chemistry Department at Hebrew University of Jerusalem. His research focuses on developmental mechanisms of inflammatory diseases and cancer, particularly studying constitutively active MAP/stress kinases (e.g., p38, ERK) and their roles in cancer and inflammation. He investigates stress-induced gene expression mechanisms in yeast and mammalian cells, focusing on transcription factors like Gcn4, Hsf1, and Msn2/4. His work also examines oncogenic transformation effects on stress-related gene expression.

Recent research demonstrated that ERK mutations induce tumor formation in Drosophila eyes, highlighting ERK's oncogenic potential. This study was presented at the 2018 ISBMB Annual Meeting and the Jerusalem Advanced School in Life Sciences.

No specific scientific awards or grants were explicitly listed in the provided texts. He supervises a research group (members not listed) and his office is located in Silberman Building - Room 517.