David Doupe

Dr. David Doupe is an Associate Professor in the Department of Biosciences at Durham University. His research focuses on understanding the regulation of epithelial stem cells, particularly in the context of cancer and tissue homeostasis. He utilizes Drosophila intestinal stem cells as a model system to study conserved signaling pathways and their roles in cell fate decisions.

• Education: Ph.D. in Biological Sciences (likely from a top institution, not explicitly stated in provided text)

Key research interests include the interplay between aging, cancer biology, and developmental processes in epithelial tissues. His work integrates genetic tools, imaging techniques, and mathematical modeling to dissect signaling dynamics and niche interactions.

Recent publications highlight studies on stem cell niche signals, collective cell migration, and systems-level analysis of signaling pathways. His work bridges basic research with implications for regenerative medicine and cancer therapy.

• Advising: Supervises five doctoral students including Alasdair Boeddinghaus (MSc), Charlotte Malpass (PhD), Emma Willington (PhD), Fanila Shahzad (PhD), and Yiming Peng (PhD).

Dr. Doupe's research group employs interdisciplinary approaches, combining molecular genetics, live-cell imaging, and computational modeling to explore fundamental questions in stem cell biology and tissue maintenance.