David C. Booth

David C. Booth is an Endowed Professor of Medicine and Director of Pulmonary Hypertension at the University of Kentucky's College of Medicine, with additional roles as Chief of Cardiology at the Lexington Veterans Affairs Medical Center. He is affiliated with the Saha Cardiovascular Research Center and CVRC. His research focuses on cardiovascular medicine, particularly pulmonary hypertension, coronary artery disease, and hemodynamic monitoring. Key contributions include studies on digoxin mortality risks (AFFIRM trial), QRS duration prognostication in atrial fibrillation, and combination therapies for pulmonary arterial hypertension.

Publications highlight expertise in cardiac imaging (IVUS), pharmacological effects (nifedipine, digoxin), and clinical trial analyses (COURAGE trial). Current work explores novel hemodynamic ratios (mixed venous oxygen saturation-to-pulmonary capillary wedge pressure) for clinical prognosis. His research integrates clinical practice with translational studies in cardiology, leveraging VA clinical data and randomized trial evidence.

• Affiliations: University of Kentucky, Lexington VAMC, Saha Cardiovascular Research Center
• Key Roles: Endowed Professor, Pulmonary Hypertension Director, Cardiology Chief
• Research Themes: Cardiac hemodynamics, arrhythmia management, interventional cardiology, drug safety