David Benjamin Konrad

David Benjamin Konrad serves as Assistant Professor at the University of Vienna within the Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences (VDS PhaNuSpo), specializing in Pharmaceutical sciences. His research laboratory is located at Josef-Holaubek-Platz 2 (UZA II), 1090 Wien, Austria.

Dr. Konrad leads an interdisciplinary research program focused on developing covalent chemical probes and drug candidates targeting advanced non-small cell lung cancer (NSCLC) and cancer-related pain. His work addresses the critical need for new therapeutic approaches against NSCLC, which accounts for 85% of all lung cancer cases and remains the leading cause of cancer-related mortality worldwide due to therapy resistance and late-stage diagnosis.

His laboratory employs (chemo)proteomics analyses to identify small molecules that target cancer vulnerabilities, using these compounds as chemical probes to study biological mechanisms and as leads for medicinal chemistry. A key innovation in his research involves developing chemical methodologies for late-stage functionalizations that leverage high-throughput experimentation and machine learning to accelerate structure-activity relationship studies.

Dr. Konrad's research bridges chemistry and biology to address the urgent clinical challenge of advanced lung cancer treatment, with particular focus on creating potent therapeutic agents with minimal off-target effects.