Dave Barefield

Dave Barefield, PhD, is an Assistant Professor in the Department of Cell & Molecular Physiology at Loyola University Chicago’s Stritch School of Medicine. His research focuses on the biophysical mechanisms underlying genetic cardiomyopathies and arrhythmias, with an emphasis on atrial dysfunction and its contributions to cardiovascular diseases. He leads the Barefield Lab, which investigates how genetic mutations and environmental factors influence disease progression.

The lab’s core project centers on the novel atrial myofilament protein Myosin Binding Protein H-like (MyBP-HL). Research employs mouse and cell culture models, complemented by computational analysis of RNA-Sequencing data and public datasets to uncover genetic links to atrial myopathy. Key interests include understanding atrial contractility’s role in cardiomyopathy and arrhythmias.

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