Daniel St Johnston

Professor Daniel St Johnston is a Bye-Fellow at the University of Cambridge, affiliated with the Gurdon Institute and the Department of Genetics. His research focuses on cell polarity, Drosophila development, and epithelial cell biology, with a particular emphasis on mechanisms governing apical-basal polarity and spindle orientation in Drosophila oocytes and midgut enterocytes.

Recent work highlights include the development of MSP-tracker/viewer software for analyzing vesicle dynamics, studies on the role of PAR protein complexes in polarity, and investigations into actin and microtubule interactions during axis formation. His research bridges genetic regulation, cytoskeletal organization, and advanced microscopy techniques.

• Key contributions to understanding epithelial polarity under energetic stress
• Development of single-molecule localization microscopy methods
• Analysis of Notch signaling and ubiquitin ligase pathways

His work has implications for cancer biology, developmental disorders, and cellular organization in complex tissues.