Daniel Leung

Daniel Leung is a Professor of Internal Medicine and Adjunct Professor of Microbiology and Immunology at the University of Utah. He holds a B.Sc. and M.Sc. from the University of British Columbia and an M.D. from Wake Forest University School of Medicine. His research focuses on Mucosal-Associated Invariant T (MAIT) cells in infections like cholera, sepsis, and diarrheal diseases, with emphasis on their immune regulatory roles and vaccine implications.

• Education:
  • B.Sc., University of British Columbia
  • M.Sc., University of British Columbia
  • M.D., Wake Forest University School of Medicine

Leung's work examines how MAIT cells contribute to B cell help, antibody production, and mucosal immunity. His team investigates these cells in human tonsil germinal centers and mouse models, particularly in cholera vaccine development using MAIT-activating ligands.

Recent publications highlight his efforts in serosurveillance for cholera and SARS-CoV-2, integrating statistical and machine learning approaches to estimate disease incidence from cross-sectional data. He also develops electronic clinical decision support tools (eCDST) for diarrhea management in low- and high-resource settings, aiming to reduce antibiotic misuse and improve patient outcomes.

Key collaborations include the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), GHESKIO (Haiti), and institutions like Johns Hopkins and University of Florida. His research is funded by NIH (R01AI130378, R01AI135114, R01AI135115) and the Bill & Melinda Gates Foundation (OPP1198876).