Cyprien Rivier

Cyprien Rivier is an Associate Research Scientist in the Department of Neurology at Yale School of Medicine. His research focuses on understanding the determinants of brain health, particularly cerebrovascular diseases and aging-related conditions such as cognitive decline and dementia. He employs integrative approaches combining multiple data layers including genetics, proteomics, epigenetics, transcriptomics, and connectomics to advance understanding of these complex neurological conditions.

His educational background includes:

• MD from University of Geneva (2020)
• MSc in Mathematics from University of Geneva (2021)

Rivier's research interests span cerebrovascular diseases, genetic epidemiology, genomic medicine, and data sciences applied to brain health. He investigates how genetic and molecular factors interact with vascular risk factors to influence stroke outcomes, cognitive decline, and dementia risk. His work often involves large-scale genomic analyses, polygenic risk scoring, and multi-omics integration to identify novel therapeutic targets and improve risk prediction models.

His recent publications demonstrate a strong focus on precision medicine approaches in stroke and dementia research, with particular emphasis on how genetic factors influence treatment response, hemorrhage risk, and long-term outcomes. The research shows increasing sophistication in integrating multiple biological data layers and social determinants of health to create comprehensive risk models.

Rivier has received notable recognition for his work:

• Ralph L. Sacco Scholarship for Brain Health (2024)
• ESOC Young Research Investigator Award in Stroke (2023)

His collaborative work with researchers including Guido J. Falcone, Kevin Sheth, Daniela Brenda Renedo, Adam de Havenon, and Santiago Clocchiatti-Tuozzo demonstrates his integration into a strong research network focused on cerebrovascular diseases and brain health. His research has significant implications for developing personalized prevention and treatment strategies for stroke and dementia.

Rivier is affiliated with Yale's Center for Brain & Mind Health, contributing to their research initiatives focused on understanding and improving brain health across the lifespan.