Cornelius Busch

Roles & Affiliation: PD Dr. med. Cornelius Busch is a Senior Physician in the Department of Anesthesiology and a Research Associate in the Section of Molecular and Translational Cardiology at Heidelberg University Hospital (UKHD). He holds a DESA (Diplom-Erweitertes Studienprogramm Arzt) and has been part of the UKHD medical team since 2008.

Education & Career:

• Studied Human Medicine at the University of Saarland, Université Pierre et Marie Curie (Paris), and the University of Zurich.
• Completed specialist training in Anesthesiology at the University Hospital Heidelberg (1999–2006).
• Habilitation (2010): Thesis on "Hypoxic Pulmonary Vasconstriction in Sepsis and Nitric Oxide-dependent Signal Transduction in Pulmonary Vasculature".
• Research Fellowship (2002–2004) at the Cardiovascular Research Center and Department of Anesthesia and Critical Care Medicine, Massachusetts General Hospital, Harvard University, Boston.

Research Focus:

• Pulmonary Inflammation and Hypoxic Pulmonary Vasconstriction.
• Gene Therapy for Right Ventricular Dysfunction in Pulmonary Hypertension.
• Role of S100A1 Protein in Diastolic Heart Failure (using spontaneously hypertensive rats as a model).
• Nitric Oxide Regulation of S100A1 Expression in Endothelial Cells.

Professional Contributions: Combines clinical expertise in anesthesiology with translational research in cardiovascular pathophysiology, focusing on mechanisms underlying pulmonary vascular diseases and therapeutic innovations.