About
Constantinos Savva is an Associate Professor in Medical Oncology at the University of Southampton, focusing on immunometabolism and metabolic reprogramming in breast cancer. He holds qualifications including an MD from the University of Ioannina, Greece, an MSc in Epidemiology from the London School of Hygiene & Tropical Medicine, and a PGCert in Clinical Bioinformatics from the University of Manchester.
- NIHR Clinical Lecturer in Medical Oncology (2022–present)
- CRUK Clinical Research Fellowship (2018)
- Member of Royal College of Physicians (2015)
His research explores how obesity, lifestyle interventions, and metabolic parameters influence tumor microenvironment dynamics in breast cancer, using techniques like targeted transcriptomics and multiplex immunohistochemistry. Recent publications highlight his work on:
- Crown-like structures (CLS) in HER2+ tumors
- Metformin's impact on immune cell infiltration
- Global cancer funding disparities
He mentors PhD students like Rachana Yadav and collaborates on projects such as CANDO-4 (sarcopenia and chemotherapy toxicity). Awards include:
- CRUK Clinical Research Training Fellowship (2018)
- Cancer Immunology Talent Fund (2021)
- BRC/NIHR Postdoctoral Bridging Fellowship (2023)
- Francis Crick Clinical Postdoctoral Fellowship (2023)
Constantinos co-leads the Research Skills module for the MSc in Cancer Biology and Immunology and tutors on the Foundation of Medicine course. His work aims to develop novel treatment strategies by integrating lifestyle interventions with immunotherapy.
