Clinton C. MacDonald

Clinton C. MacDonald, Ph.D., is a Professor in the Department of Cell Biology and Biochemistry at Texas Tech University Health Sciences Center School of Medicine. His research focuses on tissue-specific mechanisms of mRNA processing, particularly polyadenylation during spermatogenesis and brain development.

• Ph.D. in Molecular Biology and Biochemistry from State University of New York at Stony Brook
• Investigates role of τCstF-64 (Cstf2t) in male germ cell RNA processing
• Examines neuronal βCstF-64 variant functions in brain RNA regulation
• Developed assays like SLAP (Stem-Loop Luciferase Assay for Polyadenylation)

His publications (2007-2016) reveal consistent focus on RNA processing mechanisms, with key contributions to understanding testis-specific polyadenylation, neuronal RNA regulation, and RNA-binding protein functions. Articles frequently address gene knockout models, splice variants, and histone RNA processing. Grants include NIH R01 HD037109 support.