Claudia Tonelli

Claudia Tonelli is a Researcher at Cold Spring Harbor Laboratory in the laboratory of Prof. David Tuveson. She holds a PhD from the European Institute of Oncology in Milan, where she investigated p53's role in suppressing cancer development. Her research focuses on pancreatic cancer mechanisms, particularly the redox regulator Nrf2 and therapeutic target identification. She has contributed to studies on transcriptional programs in cancer and metabolic pathways critical for tumor progression.

Education: BSc from the University of Bologna, PhD at European Institute of Oncology (Dr. Bruno Amati’s group).

Research interests include pancreatic cancer biology, transcriptional regulation, DNA damage responses, and molecular oncology. Her work bridges basic science with translational research to identify novel therapeutic strategies.

Key findings from her articles highlight FGFR2 inhibition as a potential therapy, YAP/TAZ kinase dependencies, and SPDEF's role in mucinous tumors. These studies emphasize metabolic reprogramming and transcriptional networks in cancer progression.

Lab affiliation: Tuveson Lab at Cold Spring Harbor Laboratory, collaborating on pancreatic cancer interception strategies and redox biology.