Chung Wong

Chung Wong is a Professor in the Department of Chemistry and Biochemistry at the University of Missouri-Saint Louis (UMSL), affiliated with the College of Arts and Sciences. His roles include leading the Wong Group, contributing to the Center for Nanoscience, and the Biochemistry and Biotechnology Program. He joined UMSL in 2004 after academic and industrial positions at institutions like the University of Chicago, Howard Hughes Medical Institute, and SUGEN, Inc.

Education: B.Sc. (Hons.) in Chemistry and Biochemistry from the Chinese University of Hong Kong, Ph.D. in Chemistry from the University of Chicago.

Research Interests

• Computer-Aided Drug Discovery
• Molecular Simulations of Biomolecules and Biomolecular Complexes
• Computational Genomics
• Development of computational tools like EDock-ML (ensemble docking with machine learning) and SRmapper (short-read alignment)

Recent Research Trends

Focuses on ligand dissociation kinetics of kinases (e.g., GSK3β, PYK2, FAK), drug-binding mechanisms, and molecular modeling of protein-ligand interactions. Utilizes machine learning for drug discovery and advances supramolecular chemistry through studies of cyclodextrin systems.

Labs/Teams

Leads the Wong Group at UMSL, actively involved in collaborative projects across computational chemistry, biochemistry, and biotechnology. Maintains a lab (CME223) and office (CME203) in the chemistry building.