Christopher Waters

Christopher Waters is a Professor in the Department of Microbiology and Molecular Genetics at Michigan State University. His research focuses on bacterial chemical signaling pathways, particularly cyclic di-GMP (c-di-GMP) regulation in Vibrio cholerae, and developing immunotherapies for cancer. He earned his Ph.D. from the University of Minnesota and completed postdoctoral training at Princeton University.

Research interests include understanding how c-di-GMP mediates transitions between sessile biofilm and motile virulent states in pathogens. The Waters Lab also explores adenoviral delivery systems for cancer immunotherapy and bacterial phage defense mechanisms. Key projects involve biofilm heterogeneity, phenotypic segregation, and combinatorial control of biofilm development through quorum sensing and nutrient signaling.

Recent articles highlight advancements in c-di-GMP signal transduction, biofilm plasticity, and novel antibacterial strategies. Collaborations include engineering hydrogels for biofilm inhibition and developing In vivo biofilm infection models. Current efforts emphasize translating basic discoveries into clinical applications for infectious disease and cancer treatment.