Christopher R. Cederroth

Christopher R. Cederroth is an Associate Professor and Senior Researcher at the Karolinska Institutet, Department of Physiology and Pharmacology. He leads the Translational Auditory Neuroscience research group, which focuses on understanding the mechanisms of hearing loss and tinnitus to develop preventive and curative strategies. His research employs a dual approach using animal models and human genetics to identify therapeutic targets.

Research Interests:

• Molecular Mechanisms: Synaptic decoupling in the ear and homeostatic plasticity in the brain during tinnitus.
• Translational Auditory Neuroscience: Bridging basic research with clinical applications for hearing disorders.
• Genetic Epidemiology: Identifying genetic risk factors for tinnitus and hearing loss through GWAS and family studies.
• Neuroimaging & Electrophysiology: Characterizing neural signatures of tinnitus severity and auditory processing deficits.

His recent publications (2021–2025) demonstrate a strong focus on large-scale genomic studies (e.g., GBD collaborations), innovative therapeutic approaches (e.g., cochlear gene therapy), and neurophysiological characterization of tinnitus. Trends include leveraging global health datasets, advancing gene-editing techniques for hearing restoration, and exploring cortical/subcortical biomarkers for auditory pathologies.

Labs and Teams: Heads the Translational Auditory Neuroscience group at Karolinska Institutet, fostering collaborations with clinical researchers and industry partners to accelerate drug development for hearing disorders.