Christopher P. Gayer

Christopher P. Gayer, MD, PhD, is an Associate Professor of Clinical Surgery at the University of Southern California (USC). His research focuses on bile acid metabolism, particularly the role of the Farnesoid X Receptor (FXR) in intestinal barrier function and inflammation. His work spans pediatric surgical outcomes, gastrointestinal pathophysiology, and innovative diagnostic techniques such as LC-MS/MS profiling for biliary disorders.

Dr. Gayer’s recent studies address postoperative feeding protocols, enterostomy closure in low-weight infants, and the clinical implications of FXR signaling in murine models of intestinal inflammation. His research also explores pediatric trauma management, including pneumothorax intervention and cerebrovascular injury screening.

He has contributed to advancements in understanding Hirschsprung disease via colonic manometry and has published case reports on rare conditions like primary adrenal malignant rhabdoid tumors. His work emphasizes translational applications, such as plant-based nutrition’s impact on gut microbiota in chronically ill children.

Dr. Gayer’s articles highlight interdisciplinary approaches, bridging molecular biology, surgical techniques, and clinical care. His research underscores the importance of bile acid metabolism in gastrointestinal health and disease, with implications for future therapies targeting FXR pathways.