About
Christopher Douse is a Researcher and Principal Investigator at Lund University, leading research in Epigenetics and Chromatin Dynamics. He serves as Principal Investigator at both LUCC (Lund University Cancer Centre) and StemTherapy: National Initiative on Stem Cells for Regenerative Therapy. His work focuses on the epigenetic regulation of repetitive genetic elements and their impact on human brain development and disease.
His research interests center on epigenetic control of repetitive elements (genomic dark matter), chromatin regulation in stem cell models of the human brain, and the mechanisms by which repetitive genetic elements influence brain evolution, development, and degeneration. His laboratory applies biochemical and functional genomic methods to explore these questions.
Analysis of his recent publications reveals a strong focus on transposable elements, particularly retrotransposons, and their regulation through epigenetic mechanisms. His work spans chromatin structure, DNA methylation, heterochromatin formation, and the impact of these processes on neurological development and disease. The research has implications for understanding both normal brain development and neurological disorders.
Dr. Douse is actively supervising PhD students, including Carrie Davis-Hansson, and has secured significant research funding, notably from the Silicon Valley Community Foundation for his project on epigenetic control of genomic repeats in the human brain.
His collaborative network is extensive, with recent work involving researchers across multiple institutions and disciplines, reflecting the interdisciplinary nature of epigenetics and chromatin research.
