Christopher A. Cassa

Christopher A. Cassa is an Assistant Professor of Medicine at Harvard Medical School and a Geneticist at Brigham and Women's Hospital's Division of Genetics. He is also a Lecturer at Massachusetts Institute of Technology and an Associated Scientist at the Broad Institute of Harvard and MIT.

His research focuses on the statistical genetics of Mendelian disorders, particularly methods for assessing genomic variant pathogenicity and predicting clinical impacts using population-scale data and machine learning approaches. He actively contributes to clinical variant interpretation through the Brigham Genomic Medicine Program.

At MIT, he teaches courses on databases and data analytics (SCM.264) and data science/machine learning (SCM.256), with MITx versions available on edX. His program affiliations include the Medical and Population Genetics Program at the Broad Institute, Harvard Medical School Bioinformatics and Integrative Genomics PhD Program, and the Boston Evolutionary Genomics Supergroup.