About
Prof. Dr. Christian Frech serves as Head of Institute at Hochschule Mannheim, focusing on chromatographic process modeling and biopharmaceutical purification. His work addresses ion exchange chromatography, mixed-mode separations, and monoclonal antibody processing.
- Research spans mechanistic modeling of protein elution, ligand density effects, and high-loading conditions.
- Key contributions include thermodynamic frameworks and anti-Langmuir isotherm applications for bispecific antibodies.
Recent publications (2020–2023) highlight ligand density optimization, virus inactivation, and scale-up challenges in industrial chromatography. Collaborative work with Felix Wittkopp, Simon Kluters, and Yi Feng Lee demonstrates expertise in biotech process simulation.
Contact: c.frech@hs-mannheim.de
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