Christa E. Müller

Prof. Dr. Christa E. Müller is a Professor at the University of Bonn's Pharmazeutisches Institut and a member of the Transdisciplinary Research Area (TRA) 3: Life and Health Steering Committee. Her research focuses on medicinal chemistry of membrane proteins, particularly G-protein-coupled receptors (GPCRs), purinergic signaling, and ectonucleotidases. She leads two platforms: a chemical analytics platform for quantitative analysis and a compound library with synthetic molecules and natural products.

Her work integrates chemical synthesis of bioactive compounds, analytical studies, pharmacology, and molecular biology. Collaborations with biology and medicine departments enable in vivo studies. Key projects include drug design targeting GPCRs like P2Y12 and P2X receptors, as well as CD73 inhibition for cancer and inflammatory therapies.

Selected publications highlight structural studies of receptors, inhibitor development, and PET tracer applications.