Chris Spencer

Chris Spencer is a Wellcome Trust Career Development Fellow at the Nuffield Department of Medicine, University of Oxford. His research focuses on statistical genetics, with emphasis on African population genetics, malaria susceptibility (via the MalariaGEN consortium), and stratified medicine applications in hepatitis C (STOP-HCV consortium). He develops methodologies to analyze genetic determinants of host-parasite interactions and their role in disease prevention and treatment.

His work explores infectious disease impacts on human immune physiology through natural selection, aiming to translate genetic insights into clinical strategies. Recent studies include structural variation in malaria resistance genes and polymorphisms linked to pneumococcal bacteremia in Kenyan children. His computational tools, such as FINEMAP, advance variable selection in genome-wide association studies.

Publications span malaria genetics, viral resistance, and population admixture, reflecting a multidisciplinary approach to genomic medicine. Collaborations with global consortia highlight his commitment to addressing global health challenges through genetics.