Chen Li

Chen Li is a Postdoctoral Associate in Neuroscience at the Yale School of Medicine. Their research focuses on cancer immunotherapy, tumor microenvironment dynamics, and immune checkpoint inhibitors. They investigate mechanisms of immune evasion in cancers like NSCLC and glioblastoma, with a particular emphasis on biomarker discovery and therapeutic strategies. Key projects include spatial transcriptomics studies on autoimmune skin diseases and lung cancer, as well as CAR-T cell therapies targeting B7-H3 in recurrent GBM.

Research interests span immunology, oncology, and translational medicine, with publications in high-impact journals addressing PD-1/PD-L1 axis modulation, T-cell dysfunction in tumors, and the role of inflammatory pathways in diseases like lupus and fibrosis. Chen Li collaborates on preclinical and clinical studies evaluating novel immunotherapies, including anti-PD-L1 antibodies and anti-Siglec-15 agents.