Chang-Xing Ma

Chang-Xing Ma, PhD, is an Associate Professor in the Department of Biostatistics at the School of Public Health and Health Professions, University at Buffalo. He serves as Co-Director of the MPH Biostatistics Concentration. With a PhD from Nankai University (1997), his expertise spans statistical genetics, experimental design, and advanced biostatistical methods. His research focuses on developing statistical methodologies for correlated data analysis, particularly in clinical trials and public health contexts.

Dr. Ma’s work addresses challenges in analyzing paired and stratified data, including bilateral/unilateral studies in ophthalmology, pediatric care, and environmental health. Notable contributions include exact testing methods for proportion ratios, confidence interval construction for correlated outcomes, and applications in genetic epidemiology. His interdisciplinary projects integrate statistical theory with practical medical and environmental research.

Key publications explore vaccine uptake barriers among pediatric patients, frailty assessment in veterans, and the efficacy of ketamine in delirium management. He has developed SAS macros for logistic regression modeling and contributed to studies on CFTR modulation in cystic fibrosis and statin-associated muscle symptoms. His work emphasizes rigorous statistical approaches to address real-world healthcare challenges.