Chad Rienstra

Chad Rienstra is the Evelyn M. Mercer Professor of Biochemistry and Co-Director of the National Magnetic Resonance Facility at Madison, University of Wisconsin–Madison. His research focuses on advancing solid-state NMR methods for high-resolution structural biology, particularly in

• Membrane protein architecture
• Amyloid fibrillogenesis in neurodegenerative disorders
• Antifungal drug-sterol interactions
• Lipid-protein dynamics in blood coagulation

Recent publications highlight his group's innovations in

• Automated NMR optimization (2025, JACS)
• Alpha-synuclein fibril classification (2024, Nature Communications)
• Amphotericin B sterol sponge mechanisms (2021, Nature Structural & Molecular Biology)

with applications to Parkinson’s disease, drug development, and coagulation biophysics.