Carsten Hopf

Carsten Hopf is a Professor of Bioanalytics and Drug Discovery at Mannheim University of Applied Sciences, leading the Institute of Instrumental Analytics and Bioanalytics and the CeMOS (Center for Mass Spectrometry and Optical Spectroscopy). His work focuses on developing spatially resolved omics technologies (e.g., MALDI-MS imaging) for neurodegenerative and oncological research. He explores lipidomics, proteomics, and metabolomics to understand Alzheimer's disease, glioblastoma, and other neurodegenerative disorders. Key projects include the SMART-CARE-2 BMBF initiative (2023–2026) and DFG-funded research on spatial multi-omics in glioblastoma (SFB 1389).

Research interests center on mass spectrometry innovations, including matrix optimization, AI-driven data analysis, and multimodal imaging (e.g., infrared microscopy integration). His lab develops label-free cell assays for drug discovery and studies molecular mechanisms of neurodegeneration. Collaborations span academia and industry, with projects like the M²Aind partnership addressing 3D cell culture toxicity assessments.

Grants include BMBF, DFG, and EU funding for systems medicine, organoid analysis, and mass spectrometry cores. His technological advancements aim to improve biomarker discovery and translational medicine in neuro-oncology and neurodegeneration.