About
Prof. Dr. Carsten Grashoff is a faculty member at the Institute of Integrative Cell Biology and Physiology within the University of Münster. His research focuses on molecular mechanics of cell adhesion, exploring how cells sense and respond to mechanical forces through processes like cell-matrix adhesion and cell-cell adhesion. As part of his work, he has developed advanced molecular tension sensors and quantitative microscopy techniques to visualize piconewton-scale forces in living cells.
His recent publications demonstrate expertise in mechanobiological processes and optogenetic modulation of cellular forces. Key themes include integrin-talin-kindlin complexes, single-molecule super-resolution microscopy, and physiological relevance testing using mouse models. He actively contributes to interdisciplinary research networks such as Cells in Motion, Breaking Barriers (CRC 1009), and Intelligent Matter (CRC 1459).
As a member of the CiM-IMPRS graduate program and Graduate School SP BioSciences, he mentors students and early-career researchers. His team employs cutting-edge methods like TCSPC-FLIM and optogenetics to study fundamental cellular processes at the intersection of biology, chemistry, and physics.
