About
Dr. Caroline Kuo is a Professor in the Department of Pediatrics at the University of California, Los Angeles (UCLA). She holds the prestigious Pennington Family Foundation Endowed Term Chair in Pediatrics, reflecting her leadership in pediatric gene therapy research.
Dr. Kuo specializes in immunology and gene therapy for primary immune deficiencies. Her work focuses on lentiviral vectors, CRISPR-Cas9 genome editing, and hematopoietic stem cell modifications to treat conditions like Severe Combined Immunodeficiency (SCID) and X-linked hyper-IgM syndrome. Her research also explores DNA repair pathways and vector contamination impacts.
Recent publications highlight her contributions to gene therapy for ADA-deficient SCID, lentiviral approaches for chronic granulomatous disease, and DNA repair optimization in hematopoietic stem cells. Keywords include Immunology, Genetics, and CRISPR-Cas9, with subfields like Lentiviral Gene Therapy and Site-Specific Gene Editing.
Scientific Awards include the Pennington Family Foundation Endowed Term Chair in Pediatrics, recognizing her expertise in pediatric immunology and gene therapy.
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