About
Dr. Carla Horváth-Rudigier investigates metabolic regulation at ETH Zurich's Translational Nutritional Biology group. Her research examines glucose transport mechanisms in adipocytes, dietary impacts on insulin sensitivity, and molecular regulators of cholesterol biosynthesis. Her doctoral work characterized TUSC5's role in GLUT4 trafficking and natural product modulation of glucose metabolism.
Key findings include demonstrating ketogenic diets induce hepatic insulin resistance more severely than high-fat diets, and identifying Uhrf2 as a critical regulator of liver regeneration. She employs high-throughput screening, molecular biology, and metabolic phenotyping approaches.
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