About
Dr Calum Hamilton is a research academic at Newcastle University specializing in neurodegenerative disorders, with a primary focus on mild cognitive impairment (MCI) associated with Lewy bodies and Alzheimer's disease. His collaborative work spans clinical neurology, neuroscience, and geriatric psychiatry to enhance diagnostic precision and understand disease trajectories.
His research program emphasizes:
- Development of multimodal biomarkers (plasma, EEG, cardiac imaging) for early detection
- Clinical symptom profiles and progression patterns in MCI subtypes
- Neuropsychiatric manifestations and cognitive architecture differences
- Impact of comorbidities and socioeconomic factors on dementia outcomes
Analysis of his 2020-2025 publications reveals a strong focus on longitudinal cohort studies comparing Lewy body and Alzheimer's pathologies. His work consistently integrates neuroimaging, electrophysiology, and fluid biomarkers to identify predictors of dementia conversion, with significant contributions to differentiating prodromal dementia subtypes through quantitative EEG, cardiac scintigraphy, and free water imaging techniques.