About
C. Cabrele is a researcher at the University of Salzburg, Faculty of Natural and Life Sciences, specializing in organic and bioorganic chemistry applied to protein research. Her work focuses on understanding protein function in health and disease, particularly through the design of synthetic peptides and chemical modulators.
- Targeting Id family helix-loop-helix (HLH) transcription factors involved in cancer and cellular differentiation
- Developing peptide-based therapeutics with enhanced stability and specificity for G-protein coupled receptors (GPCRs)
- Investigating protein conformational behavior under varying environmental conditions
- Collaborating with international institutions on polymer functionalization and biomaterials
Her research integrates chemical synthesis, structural analysis, and interdisciplinary approaches to address challenges in disease diagnosis and therapy. Publications span topics including protein dimerization, conformational switch motifs, and nanoparticle-receptor interactions.
Key collaborations include:
- University of Padova and University of Regensburg on PTH/NPY analogs
- Prof. B. König on artificial metal receptors
- Excellence Cluster RESOLV on protein solvation
- Prof. Gianluca Ciardelli (Politecnico di Torino) on smart polymers
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