Bruno Conti

Bruno Conti is an Adjunct Professor at Yale School of Medicine, Professor at the San Diego Biomedical Research Institute, Emeritus Professor at Scripps Research, and Adjunct Professor at Stockholm University. His research focuses on aging, age-associated neurodegeneration, and the neuroimmunology of cytokines. He has held positions at multiple institutions, including New York Medical College and Cornell University, before joining The Scripps Research Institute.

Education: Bruno Conti completed his studies in Italy, followed by training in Immunology at New York Medical College and Neuroscience at Cornell University.

Research Interests: Conti’s work explores how body temperature and calorie restriction influence longevity, identifying molecular pathways linking these factors. He investigates cytokines such as interleukin-18 (cloned in his lab) and interleukin-13, which play roles in neuroimmunomodulation and Parkinson’s disease pathology. His studies aim to develop "temperature mimetics" targeting these pathways to address aging and neurodegenerative conditions.

Scientific Contributions: Conti’s research has demonstrated that reduced core body temperature extends lifespan independent of calorie intake, and identified key molecules mediating this effect. He also revealed interleukin-13’s role in dopaminergic neuron loss in Parkinson’s disease.

Labs/Teams: His research is conducted through collaborations at affiliated institutions, focusing on interdisciplinary teams in aging biology and neuroimmunology.