Brian O Smith

Dr. Brian O Smith is a Senior Lecturer in the School of Molecular Biosciences at the University of Glasgow. His research group specializes in applying NMR spectroscopy to determine macromolecular structures and investigate protein-nucleic acid interactions. Key infrastructure includes a 600 MHz NMR spectrometer with cryoprobe capabilities.

Research focuses on:

• NMR methodology development for solution-state structural analysis
• Natural surfactant proteins (ranaspumins, latherin) and their biotechnological applications
• Parasitic nematode lipid-binding proteins (FARs, NPAs) as therapeutic targets
• Epigenetic regulation mechanisms through histone/DNA modification recognition
• UV-B perception via plant UVR8 photoreceptors

Recent publications demonstrate consistent focus on protein structure-function relationships, ubiquitin system mechanics, and novel biochemical techniques. Collaborative networks include researchers at University of Edinburgh, UNC Chapel Hill, and INIBIOLP Argentina.