Brent Fogel

Dr. Brent Fogel is a Professor in the Departments of Neurology and Human Genetics at the David Geffen School of Medicine, UCLA. He directs the Neurogenetics Clinic and the UCLA Clinical Neurogenomics Research Center, focusing on diagnosing and managing genetic neurological disorders such as cerebellar ataxia, ataxia with oculomotor apraxia, spastic paraplegia, and leukodystrophies. His research integrates genomics, bioinformatics, and neuroimaging to improve precision medicine in prenatal counseling and rare disease diagnosis.

• Education:
  • MD, PhD from Medical College of Wisconsin (2003)
  • PhD in Genetics (2001)
  • Internship in Internal Medicine (Northwestern University, 2004)
  • Residency in Neurology (UCLA, 2007)
  • Fellowship in Neurogenetics (UCLA, 2009)
  • Board Certified in Neurology (2009)

Research Focus: Dr. Fogel’s work spans neurogenetics, spinocerebellar ataxia, leukodystrophy, and genomic technologies. He has pioneered gene discovery in hereditary ataxias, developed transcriptional biomarkers, and contributed to diagnostic guidelines for rare disorders. His studies on lysosomal genes in Parkinson’s disease and exome sequencing disparities address critical gaps in neurogenetic research.

Key Collaborations: He leads multicenter studies with the Ataxia Global Initiative, Undiagnosed Diseases Network, and Genomics England Research Consortium. His lab (FogelLab) develops tools like multiWGCNA for gene network analysis.