Berend Isermann

Professor Berend Isermann is a Professor of Laboratory Medicine at Leipzig University, affiliated with the Faculty of Medicine. He leads research into thrombo-inflammation mechanisms, focusing on molecular pathways linking coagulation and inflammation in diseases such as diabetes, kidney failure, and cardiovascular conditions. His work has earned prestigious recognition, including the ERC Advanced Grant (2024) for a project investigating molecular switches in thrombo-inflammation.

Education: Studied medicine at Würzburg (Germany), Bristol (UK), and New Haven (USA). Completed specialist training in internal medicine, endocrinology, and laboratory medicine at Heidelberg University Hospital. Previously held professorships at the Universities of Magdeburg (2011–2019) and Leipzig (2019–present).

Research interests center on understanding how thrombo-inflammation drives diseases like preeclampsia, chronic kidney disease, and complications from infections like COVID-19. Key projects include studying tissue factor’s role in inflammation-coagulation cross-talk, microglial-brain interactions in chronic kidney disease, and developing therapies targeting molecular switches.

Scientific achievements include discovering tissue factor’s complex with inflammatory regulators, published in high-impact journals, and advancing methods to measure thrombo-inflammatory biomarkers. His interdisciplinary team at Leipzig Medical Center explores therapeutic strategies to control thrombo-inflammation across multiple organ systems.

Awards: ERC Advanced Grant (2024) valued at €2.5 million for five years of research into molecular mechanisms of thrombo-inflammation.

Grants and collaborations: ERC-funded project involves analyzing molecular switches in heart disease, obesity, and cancer models. His work bridges basic science and clinical translation, with a focus on kidney-brain interactions and diet-based interventions like the green-Mediterranean diet’s epigenetic effects.

Labs/Teams: Leads a cross-departmental team at Leipzig University Medical Center integrating immunology, nephrology, and cardiology research. Collaborates on projects involving placental thrombo-inflammation, anticoagulant drug effects, and machine learning applications in diagnostics.