About
Dr. Begoña García Ruiz is a Professor in the Department of Chemistry at the University of Burgos, Spain, where she leads research in bioinorganic chemistry with a focus on metal-based therapeutic agents. Her academic career spans over a decade with consistent high-quality publications in top chemistry journals.
Her research interests center on the design, synthesis, and characterization of metal complexes—particularly platinum, ruthenium, rhodium, and iridium compounds—and their interactions with nucleic acids. She specializes in studying how these complexes bind to DNA structures, especially G-quadruplexes, and how this binding relates to anticancer and antibacterial activity. Her work bridges inorganic chemistry, biochemistry, and pharmacology to develop novel therapeutic approaches.
Analysis of her recent publications (2020-2022) reveals a strong focus on structure-activity relationships in metal complexes, with particular attention to how ligand modifications affect biological activity. Her research shows increasing sophistication in targeting specific DNA structures and understanding the mechanistic basis for cytotoxicity.
Dr. García Ruiz maintains an active research program with numerous collaborations both within Spain and internationally, as evidenced by her co-authorship with researchers from Germany, Italy, France, and the UK. Her work demonstrates consistent productivity with multiple publications each year across high-impact journals in chemistry and biochemistry.
She actively supervises doctoral students, with several completed theses focusing on metal complex interactions with nucleic acids. Her mentorship spans both experimental and theoretical aspects of bioinorganic chemistry, preparing students for careers in academic and industrial research settings.
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