
Athanassios G. Siapas
Professor · Systems Neuroscience
California Institute of Technology (Caltech)About
Athanassios G. (Thanos) Siapas is a Professor of Computation and Neural Systems at the California Institute of Technology (Caltech). He holds the Bren Scholar distinction (2003-2008) and served as Executive Officer of the Computation and Neural Systems department from 2017-2020. His research focuses on understanding neural network mechanisms underlying learning and memory, particularly the interplay between hippocampal and neocortical circuits during memory consolidation. His work employs multi-electrode recordings, two-photon imaging, and theoretical models to study neuronal interactions in awake animals.
Key achievements include developing novel neural recording technologies and being named a Vannevar Bush Faculty Fellow (2015) and recipient of the NIH Pioneer Award (2011). He teaches core courses such as CNS 100 and advanced topics in systems neuroscience. Current projects include investigating hippocampal CA3 dynamics during ripples, subthreshold membrane potential fluctuations, and the role of inhibition in memory processing.
His lab's interdisciplinary approach combines experimental neuroscience with computational methods, aiming to bridge gaps between neural circuits and cognitive functions. Ongoing efforts focus on advancing neurotechnology for dense 3D brain recordings and understanding cortical-hippocampal coordination during memory formation.
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