Antoine Toubert

Prof. Antoine Toubert serves as Professor of Immunology at University of Paris-Diderot and Hôpital Saint-Louis in Paris, an institution historically renowned for HLA discovery (Jean Dausset) and first cord blood transplantation (Eliane Gluckman). His dual academic-clinical role positions him at the forefront of translational immunology research.

His primary research focuses on immune cell dynamics in hematologic disorders, particularly natural killer (NK) and T cell biology in myelodysplastic syndromes (MDS), acute leukemia, and autoimmune conditions. Key investigations include 3D marrow organoid systems for immune cell generation, genetic mutation impacts (TET2) on NK function, and T cell mechanisms in Crohn's disease. Clinical work emphasizes haploidentical stem cell transplantation with engineered T cells (Rivo-cel) and lymphopenia as a prognostic factor in MDS.

Recent publications reveal strong trends in leveraging engineered cellular therapies for immune reconstitution and developing organoid models to dissect immune-epithelial interactions. His work bridges fundamental immunology with clinical applications in transplantation and hematologic malignancies, showing particular emphasis on prognostic biomarkers and innovative cell-based interventions.

Prof. Toubert contributes significantly to academic discourse as Specialty Chief Editor for Alloimmunity and Transplantation at Frontiers in Immunology and Topic Editor for immune cell therapy approaches targeting tumor microenvironments. His editorial leadership complements his active research in cellular immunology and transplantation medicine.