Anne Bowcock

Dr. Anne Bowcock is a Professor in Oncological Sciences, Dermatology, and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai. She previously held positions at Imperial College London and Washington University Medical Center. Her research focuses on cancer genomics and inflammatory skin diseases, particularly psoriasis and psoriatic arthritis. She identified key genes like CARD14 (linked to psoriasis) and BAP1/SF3B1 (critical for uveal melanoma progression). Her lab uses genomic, epigenomic, and functional approaches to study disease mechanisms.

• Education: PhD from the University of the Witwatersrand; Postdoc at Stanford University.
• Awards: 2005 American Skin Association Psoriasis Achievement Award, Medical Research Council Award (1981).

Research interests include molecular drivers of cancers (e.g., uveal melanoma, acral melanoma) and genetic basis of skin disorders. She investigates small RNAs, noncoding RNAs, and therapeutic interventions for psoriasis. The lab also explores tumor heterogeneity and metastasis mechanisms in uveal melanoma using organoid models.

Key articles highlight discoveries in cancer genetics and psoriasis pathogenesis. Her team includes postdoctoral fellows, bioinformaticians, and collaborators across disciplines.