Ann Valentine

Ann Valentine is a Professor and Department Chair at Temple University's Department of Chemistry within the College of Science and Technology. Her research specializes in bioinorganic chemistry, particularly focusing on biologically relevant metals such as iron and titanium. Her investigations span metal uptake mechanisms, therapeutic applications of metal complexes, and biomineralization processes.

Research Interests:

• Metal homeostasis in biological systems
• Development of titanium-based therapeutics
• Nanoparticle-biomolecule interactions
• Biomineralization mechanisms
• Environmental fate of engineered nanomaterials

Her recent publications demonstrate a strong focus on titanium biochemistry, nanoparticle interactions, and microbial metal processing. Research trends include advanced characterization of metal-biomolecule complexes, nanomaterial environmental impacts, and development of metal-based therapeutics. Computational and experimental approaches are combined to study metal speciation and reactivity in biological contexts.

Scientific Awards:

• American Cancer Society Research Scholar Award
• Paul D. Saltman Award for Metals in Biology
• Lindback Distinguished Teaching Award
• ACS PROGRESS/Dreyfus Lectureship Award
• Chemical Pioneer Award

As principal investigator of the Valentine Lab, she mentors graduate and undergraduate researchers in bioinorganic chemistry. Current research is supported by grants including an NIH R01 from NIGMS. The lab utilizes spectroscopic, microbiological, and nanomaterial characterization techniques to investigate metal processing in biological systems.

Laboratory Focus:

• Spectroscopic analysis of metalloproteins
• Microbial metal transformation studies
• Nanoparticle synthesis and characterization
• Molecular mechanisms of metal homeostasis