Anil Chandraker

Anil Chandraker, MD is a Professor and the Jack M. Wilson Chair in Biomedical Research at UMass Chan Medical School, Department of Medicine, within the T.H. Chan School of Medicine. His research focuses on kidney transplantation immunology, biomarkers for rejection, and clinical management of transplant recipients. Dr. Chandraker completed his MBBS at the University of Glasgow, United Kingdom.

Education:

• MBBS, University of Glasgow, United Kingdom

Research Interests: Dr. Chandraker’s work centers on advancing kidney transplantation outcomes through innovations in immune monitoring, biomarker development (e.g., exosomal mRNA tests for rejection), and personalized immunosuppression strategies. His lab explores mechanisms of antibody-mediated rejection, BK viremia management, and translational approaches to reduce allograft dysfunction. He has pioneered studies in exosome-based diagnostics and cellular therapies.

Key Contributions:

• Developed urine-based exosome tests for early kidney transplant rejection detection
• Investigated APOL1 gene variants’ impact on transplant outcomes
• Conducted clinical trials for BK viremia therapies and immunosuppressant optimization
• Advanced understanding of metabolic pathways in transplant rejection

Labs/Teams: His research integrates with the Transplantation Biology Group at UMass Chan, collaborating on clinical and translational studies. He leads interdisciplinary teams addressing immune tolerance and biomarker discovery in solid-organ transplantation.