Angom Ramcharan S. Angom

Assistant Professor · Vascular dysfunction and remodeling

Mayo Clinic College of Medicine and Science

United States

About

Angom Ramcharan S. Angom, Ph.D. is an Assistant Professor in the Department of Biochemistry and Molecular Biology at Mayo Clinic in Jacksonville, Florida. His research focuses on vascular biology, particularly the role of VEGF receptors (VEGFR-1) and neuropilin (NRP-1) signaling in heart regeneration, aging, and stroke.

Uses genetically engineered zebrafish and mouse models to study vascular remodeling
Investigates molecular mechanisms in brain endothelial cell senescence
Examines VEGF-B/NRP-1/VEGFR-1 axis in myocardial infarction and cardiac hypertrophy
Develops tumor-targeted therapies for glioblastoma resistance

Research Impact: Addresses clinical challenges in heart failure, vascular dementia, and glioblastoma treatment resistance through mechanistic studies and therapeutic development.

Scientific Awards

Innovation in Aging Award (Mayo Clinic, 2024-2025)
Ted and Loretta Rogers Cardiovascular Career Development Award (2023-2024)
Indian Council of Medical Research Senior Research Fellowship (2012-2015)

Editorial Roles: Associate Editor (Frontiers in Pharmacology), Editor (Cancer Report), and Guest Editor for multiple journals.

Research fields

Vascular dysfunction and remodeling Cardiovascular diseases Cerebrovascular conditions Vascular endothelial growth factor (VEGF) signaling Neuropilin (NRP-1) signaling Heart regeneration Aging-related endothelial cell dysfunction Stroke research Cardiac homeostasis and pathology Glioblastoma therapy Sex-specific differences in cancer outcomes

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