Angela Mitchell

Angela Mitchell is an Assistant Professor at Texas A&M University. She holds a B.S. in Biotechnology from Elizabethtown College (2008), a Ph.D. in Microbiology and Immunology from the University of North Carolina at Chapel Hill (2013), and completed postdoctoral research at Princeton University’s Department of Molecular Biology (2014–2019). Her research focuses on understanding mechanisms that strengthen the outer membrane (OM) permeability barrier of gram-negative bacteria during stress, with particular emphasis on antibiotic resistance and pathogenesis.

Her work employs genetics and biochemistry to investigate changes in the OM during stress, mechanisms reinforcing the barrier, and their roles in antibiotic resistance. Key areas include phospholipid transporters, envelope stress responses (e.g., CpxAR system), and lipopolysaccharide integrity. The Mitchell Lab also explores novel inhibitors targeting OM proteins like BamA.

Publications highlight contributions to phospholipid flow regulation (YhdP protein), copper homeostasis links in E. coli pathogenesis (YhiM protein), and the functional diversification of phospholipid transporters. Her findings bridge fundamental microbiology with clinical challenges posed by antibiotic-resistant bacteria.

Lab and office spaces are located in the BSBE building (301A for office, 308 for lab). No awards or grants are explicitly listed in the provided materials. The Mitchell Lab website offers further details on ongoing projects and collaborations.