Andy Howden

Dr. Andy Howden serves as a Principal Investigator and Lecturer (Teaching and Research) in the Cell Signalling and Immunology group within the School of Life Sciences at the University of Dundee. With an h-index of 23 and 2199 citations, his research program is well-established in the fields of quantitative proteomics and immune cell biology.

Dr. Howden's research focuses on using quantitative proteomics and protein biochemistry to provide molecular understanding of how immune cells sense and respond to their environment. He has a specific interest in T and B lymphocytes and their links to neurodegenerative diseases. His recent work investigates kinase signaling pathways, particularly Leucine-rich Repeat Kinase 2 (LRRK2), and how these relate to conditions like Parkinson's and Crohn's disease, as well as immune cell metabolism and autophagy regulation.

His recent publications (2024-2025) demonstrate strong output in high-impact journals including Nature Communications, Nature Immunology, and EMBO Reports, with research spanning immunology, proteomics, and neurodegenerative disease mechanisms. These works reveal consistent themes in immune cell signaling, metabolic regulation, and the molecular connections between inflammation and neurological conditions.

• Active investigator on 'Immune cell profiling and quality control position' project (2025-2026)
• Previously involved in Rapid Research in Covid-19 Programme (2020-2021)
• Regularly serves as grant reviewer for MRC projects

As an educator, Dr. Howden manages the Level 3 Cell Signalling (BS32006) and Level 4 Advanced Cell Signalling (BS42013) modules, and lectures in Level 3 Immunology (BS32009). He is actively involved in the Dundee Research Interest Group and has organized outreach events including the Open Doors Day Event. His ORCID profile (0000-0002-4332-9469) documents his extensive research contributions across immunology and cell signaling disciplines.