Andrew Modzelewski
Assistant Professor · Retrotransposon Reactivation
University of PennsylvaniaAbout
Andrew Modzelewski, Ph.D., is an Assistant Professor of Molecular Biology at the University of Pennsylvania School of Veterinary Medicine. His research focuses on retrotransposon reactivation in mammalian development and disease, particularly during preimplantation embryogenesis and in pathological states like cancer.
- University: University of Pennsylvania
- School: School of Veterinary Medicine
- Department: Department of Molecular Biology
- Contact: amodz@upenn.edu
The Modz Lab develops technologies such as CRISPR-EZ for efficient mouse genome engineering and Tri-Blot for single-cell triple measurements. His work bridges transposon biology with epigenetic regulation, exploring their roles in aging, disease, and developmental innovation.
Recent publications highlight his contributions to understanding retrotransposon-driven developmental mechanisms, CRISPR-EZ optimization, and transposon domestication in genomic evolution. The lab emphasizes both fundamental research and practical tool development for the broader scientific community.
Located at 380 S. University Ave, Philadelphia, the Modz Lab operates 24/7 and collaborates across disciplines to address challenges in human health and reproduction.
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