Anders Castor

Anders Castor is a Physician Scientist and Specialist Physician in Pediatrics at Lund University's Faculty of Medicine, Department of Pediatrics. His primary affiliation is with the Lund University Cancer Centre (LUCC), where he focuses on pediatric hematology-oncology research, particularly acute lymphoblastic leukemia (ALL). Castor maintains active clinical and research roles, contributing significantly to the understanding of genetic and molecular mechanisms in childhood cancers.

• Institution: Lund University
• School: Faculty of Medicine
• Department: Department of Pediatrics
• Research Center: Lund University Cancer Centre (LUCC)

Castor's research primarily centers on acute lymphoblastic leukemia in children, with particular emphasis on genetic and genomic aspects. His work spans from basic molecular characterization of leukemia subtypes to clinical applications in precision medicine. He investigates mutational signatures, chromatin accessibility, and genetic variants that influence disease development, progression, and treatment response in pediatric ALL. His research bridges laboratory findings with clinical applications, particularly through the iCOPE project focused on childhood oncology precision medicine.

His recent publications demonstrate a strong focus on the intersection of genomics and clinical oncology, with particular attention to DUX4-rearranged cases, KMT2A-rearranged leukemias, and ARID5B variants in pediatric ALL. Castor's work increasingly incorporates ethical considerations in pediatric cancer research, as evidenced by his qualitative study on children's values and moral dilemmas during cancer treatment.

Castor has been actively involved in multiple significant research projects including iCOPE (the interregional Childhood Oncology Precision medicine Exploration), LUC3 (Lund University Child Centered Care), and various studies on hospital-based home care for children with long-term illnesses. His collaborative network extends across multiple institutions and disciplines, reflecting the interdisciplinary nature of modern pediatric cancer research.

• Active participation in 5 major research projects between 2009-2022
• Speaker at the LUCC - Child: Acute Lymphoblastic Leukemia (ALL) Seminar in 2021
• Extensive collaboration with researchers across pediatric oncology, genetics, and ethics